CMMB 403 Final Q&A Latest Update
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CMMB
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CMMB
CMMB 403 Final Q&A Latest Update
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| Uploaded on: | May 2, 2025 |
| Last updated: | May 3, 2025 |
| Number of pages: | 68 |
| Written in: | 2025/2026 |
| Type: | Exam (elaborations) |
| Contains: | Questions & Answers |
| Tags: | CMMB 403 Final Q&A Latest Update |
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CMMB 403 Final | Q&A Latest 2025/2026 | 100% PASS What is the developmental gene hierarchy in drosophila? What do each of them do? Give all examples for each 1. Maternal effect genes: set up early polarity (bicoid, nanos, caudal, hunchback) 2. Gap genes: Create 1-2 large general regions (Kruppel, knirps, giant, hunchback) 3. Pair-rule: Create 7 segments (even-skipped, Paired, Fushi tarazu) 4. Segment polarity: Give all 14 segments polarity (Engrailed, SHH, wingless) 5. Hox genes: Give unique identity to all segments and designate formed structures (Antennapedia, Ultrabithorax) Describe the phenotypes seen in drosophila embryos if different hierarchal genes are knocked out Maternal: Loss of whole region (no head) Gap: multiple sequential segments are missing Pair: every other segment is missing (7 segments form)
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